Rising to the Challenge: CNPRC’s Role in Combatting Dengue Virus in 2024

In 2024, there has been a record-breaking number of dengue virus outbreaks, with more than seven million cases documented. Dengue virus is a viral infection that spreads from mosquitoes to humans, resulting in symptoms such as high fever, headache, nausea, body aches, and rash. In severe cases or cases of reinfection, dengue virus can be fatal.

The need for an inclusive vaccine or viable treatment option is paramount. A report by NBC News on May 28th, 2024, highlighted the escalating prevalence of mosquitoes capable of carrying the Dengue Virus in the United States, attributed to climate change. It advised individuals to exercise caution in regions where mosquitos carrying Dengue may be present.

In response to the evolving health crisis posed by the Dengue Virus, CNPRC researchers are diligently working on solutions. Scientists in our Infectious Disease unit recently concluded a study involving 20 rhesus macaques, testing the efficacy and durability of a newly developed vaccine for Dengue Virus. This study marks a significant step towards creating a vaccine that is safe for all age groups and can be distributed to more remote populations.

In addition to the urgent need for a vaccine, as of now, there is no specific therapy available for Dengue Virus infection apart from supportive care. CNPRC has initiated a new collaboration aimed at obtaining approval for a treatment for Dengue Virus infection in humans. Researchers are currently preparing a series of experiments to assess the safety and effectiveness of new antiviral drugs designed to treat Dengue Virus infections.

As the record-breaking number of Dengue Virus cases in 2024 continues to climb, the need for an inclusive vaccine and viable treatment options becomes increasingly necessary. CNPRC researchers are making significant strides in this effort, with promising vaccine studies and ongoing collaborations aimed at developing antiviral treatments. These initiatives are crucial steps toward combating the Dengue Virus and safeguarding global health.