sample

Search Publication

2025

Safety and biocompatibility of a novel biodegradable aflibercept-drug delivery system in rhesus macaques

Story BD, Park S, Roszak K, Shim J, Motta M, Ferneding M, Rudeen KM, Blandino A, Ardon M, Le S, Teixeira LBC, Yiu G, Mieler WF, Thomasy SM, Kang-Mieler JJ. Safety and biocompatibility of a novel biodegradable aflibercept-drug delivery system in rhesus macaques. Drug Deliv. 2025 Dec;32(1):2460671. doi: 10.1080/10717544.2025.2460671. Epub 2025 Mar 4. PMID: 40038090; PMCID: PMC11884103.

Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections.

Rocha CS, Alexander KL, Herrera C, Weber MG, Grishina I, Hirao LA, Kramer DJ, Arredondo J, Mende A, Crakes KR, Fenton AN, Marco ML, Mills DA, Kappes JC, Smythies LE, Ziprin P, Sankaran-Walters S, Smith PD, Dandekar S. Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections. Mucosal Immunol. 2025 Jan 31:S1933-0219(25)00011-X. doi: 10.1016/j.mucimm.2025.01.011. Epub ahead of print. PMID: 39894082.

In vivo evolution of env in SHIV-AD8EO-infected rhesus macaques after AAV-vectored delivery of eCD4-Ig.

O'Hagan D, Shandilya S, Hopkins LJ, Hahn PA, Fuchs SP, Martinez-Navio JM, Alpert MD, Gardner MR, Desrosiers RC, Gao G, Lifson JD, Farzan M, Ardeshir A, Martins MA. In vivo evolution of env in SHIV-AD8EO-infected rhesus macaques after AAV-vectored delivery of eCD4-Ig. Mol Ther. 2025 Feb 5;33(2):560-579. doi: 10.1016/j.ymthe.2024.12.015. Epub 2024 Dec 12. PMID: 39673132; PMCID: PMC11853013.

2024

Evaluation of registration-based vs. manual segmentation of rhesus macaque brain MRIs. Brain Struct Function

Charbonneau JA, Davis B, Raven EP, Patwardhan B, Grebosky C, Halteh L, Bennett JL, Bliss-Moreau E. Evaluation of registration-based vs. manual segmentation of rhesus macaque brain MRIs. Brain Struct Funct. 2024 Nov;229(8):2029-2043. doi: 10.1007/s00429-024-02848-7. Epub 2024 Aug 13. PMID: 39136727; PMCID: PMC11483197.

Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease. Alzheimers Dementia.

Beckman D, Diniz GB, Ott S, Hobson B, Chaudhari AJ, Muller S, Chu Y, Takano A, Schwarz AJ, Yeh CL, McQuade P, Chakrabarty P, Kanaan NM, Quinton MS, Simen AA, Kordower JH, Morrison JH. Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease. Alzheimers Dementia. 2024 Aug;20(8):5198-5219. doi: 10.1002/alz.13868. Epub 2024 Jun 21. PMID: 39030748; PMCID: PMC11350056.

Evaluation of registration-based vs. manual segmentation of rhesus macaque brain MRIs

Charbonneau JA, Davis B, Raven EP, Patwardhan B, Grebosky C, Halteh L, Bennett JL, Bliss-Moreau E. Evaluation of registration-based vs. manual segmentation of rhesus macaque brain MRIs. Brain Struct Funct. 2024 Nov;229(8):2029-2043. doi: 10.1007/s00429-024-02848-7. Epub 2024 Aug 13. PMID: 39136727; PMCID: PMC11483197.

Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity.

Otero CE, Petkova S, Ebermann M, Taher H, John N, Hoffmann K, Davalos A, Moström MJ, Gilbride RM, Papen CR, Barber-Axthelm A, Scheef EA, Barfield R, Sprehe LM, Kendall S, Manuel TD, Vande Burgt NH, Chan C, Denton M, Streblow ZJ, Streblow DN, Hansen SG, Kaur A, Permar S, Früh K, Hengel H, Malouli D, Kolb P. Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity. bioRxiv [Preprint]. 2024 Feb 28:2024.02.27.582371. doi: 10.1101/2024.02.27.582371. Update in: Nat Commun. 2025 Jan 31;16(1):1200. doi: 10.1038/s41467-025-56419-3. PMID: 38464092; PMCID: PMC10925275.

Spontaneous natural killer cell lymphoproliferative disorder in a rhesus macaque

Barro MV, Garzel LM, Keesler RI, Casey KM, Olstad KJ. Spontaneous natural killer cell lymphoproliferative disorder in a rhesus macaque. J Vet Diagn Invest. 2025 Jan;37(1):155-159. doi: 10.1177/10406387241297087. Epub 2024 Dec 4. PMID: 39630285; PMCID: PMC11618834.

Nebulized vasopressin penetrates CSF and improves social cognition without inducing aggression in a rhesus monkey model of autism.

Talbot CF, Oztan O, Simmons SMV, Trainor C, Ceniceros LC, Nguyen DKK, Del Rosso LA, Garner JP, Capitanio JP, Parker KJ. Nebulized vasopressin penetrates CSF and improves social cognition without inducing aggression in a rhesus monkey model of autism. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2418635121. doi: 10.1073/pnas.2418635121. Epub 2024 Nov 25. PMID: 39585977; PMCID: PMC11626171.

Lipid nanoparticle-mediated mRNA delivery to CD34+ cells in rhesus monkeys

Kim H, Zenhausern R, Gentry K, Lian L, Huayamares SG, Radmand A, Loughrey D, Podilapu AR, Hatit MZC, Ni H, Li A, Shajii A, Peck HE, Han K, Hua X, Jia S, Martinez M, Lee C, Santangelo PJ, Tarantal A, Dahlman JE. Lipid nanoparticle-mediated mRNA delivery to CD34+ cells in rhesus monkeys. Nat Biotechnol. 2024 Nov 22. doi: 10.1038/s41587-024-02470-2. Epub ahead of print. PMID: 39578569.