Germline-targeting HIV Envelope SOSIP immunization more frequently elicits broadly-neutralizing antibody precursor responses in infant compared to juvenile rhesus macaques

Issah YA, Hu X, Isaac J, Shen X, Davis D, Ozorowski G, Sewall LM, Zhang S, Kang E, Vuong K, Dennis M, Chen JL, Ramos JM, Yasmeen A, Eudailey J, Cupo A, Weinbaum C, Gao H, Stanfield-Oakley S, Ferrari G, Klasse PJ, Fouda G, Hudgens M, Ward AB, Montefiori DC, Sanders RW, Moore JP, Van Rompay KKA, De Paris K, Permar SR, Nelson AN.bioRxiv [Preprint]. Germline-targeting HIV Envelope SOSIP immunization more frequently elicits broadly-neutralizing antibody precursor responses in infant compared to juvenile rhesus macaques. 2025 May 30:2025.05.27.656273. doi: 10.1101/2025.05.27.656273. PMID: 40501834