Engineered IgM and IgG cleaving enzymes for mitigating antibody neutralization and complement activation in AAV gene transfer

Smith TJ, Elmore ZC, Fusco RM, Hull JA, Rosales A, Martinez M, Tarantal AF, Asokan A.Mol Ther. Engineered IgM and IgG cleaving enzymes for mitigating antibody neutralization and complement activation in AAV gene transfer. 2024 Jul 3;32(7):2080-2093. doi: 10.1016/j.ymthe.2024.05.004. Epub 2024 May 7.PMID: 38715362 

Year of Publication
2024