Anatomic and Clinical Pathology
Primate Anatomic and Clinical Pathology Services (ACPS) has extensive expertise in clinical, gross, and microscopic diagnostic pathology to support multidisciplinary research in human health and disease. It promotes colony health and disease surveillance to ensure the highest level of health in our research animals.
ACPS also provides research support for projects requiring pathology expertise, and maintain and administers valuable resources which are used by an extensive network of investigators at UC Davis, locally, and nationally.
Contributing to Human and Animal Health
- The pathologists in ACPS are working to characterize common diseases in nonhuman primates to enhance colony health and contribute to veterinary medical knowledge
- The staff also identifies and characterizes spontaneous nonhuman primate disease that may be used as models of human disease
- They have the ability to integrate information gathered at necropsy with clinical, genetic, and behavioral data, which has the potential to shed new light on the pathogenesis of disease processes, identify phenotypes that may not be immediately apparent with a single discipline approach.
- ACPS staff also collaborate with investigators within the CNPRC as well as throughout the country to provide pathology support and expertise.
Biospecimen Distribution Program
- This program distributes tissue samples as well as other biological samples upon request
- Samples can be collected and prepared according to the investigators’ needs
- Additionally, a highly organized archive of formalin-fixed and paraffin blocked tissues and glass slides are housed in air conditioned spaces. The catalogued database of this archive allows for easy retrieval of requested samples.
Teaching and Training
- Once a month, the ACPS teleconferences with pathologists from other NPRCs and nonhuman primate research institutes from across the country. Unique cases that have occurred in the animals are presented in slides and the case history is discussed
- ACPS personnel provide teaching and training across many different sectors, but most notable is the highly sought-after laboratory animal pathology postdoctoral training program in conjunction with the UC Davis School of Veterinary Medicine
- The ACPS has an extensive collection of digital images for education
A team of 5 veterinary and anatomic pathologists use their range of collaborative expertise and a total of more than 60 years of combined expertise to provide outstanding pathology services. Additionally, the Clinical Laboratory is headed by a highly experienced medical laboratory scientist who has more than 32 years experience analyzing nonhuman primate samples.
Chen EC, Yagi S, Kelly KR, Mendoza SP, Tarara RP, Canfield DR, Maninger N, Rosenthal A, Spinner A, Bales KL, Schnurr DP, Lerche NW, and Chiu CY. Cross-species transmission of a novel adenovirus associated with a fulminant pneumonia outbreak in a new world monkey colony. PLoS Pathog 7:e1002155, 2011. PMCID: PMC3136464, PMID 21779173