Infectious Diseases

Experimental COVID-19 Vaccine Offers Long-Term Protection Against Severe Disease

Experimental COVID-19 Vaccine Offers Long-Term Protection Against Severe Disease Two-dose vaccines provide protection against lung disease in rhesus macaques one year after they were vaccinated as infants, a new study shows. The work, published in Science Translational Medicine Dec. 1, is a follow-up to a 2021 [...]

2024-01-19T12:45:52-07:00December 2nd, 2022|

Antibiotic Exposure During Infancy Remodels Immune Response to Respiratory Pathogens

Antibiotic Exposure During Infancy Remodels Immune Response to Respiratory Pathogens Infants are commonly exposed to and treated with antibiotics during the birthing process. However, new research in nonhuman primates may change the way doctors approach antibiotic treatment. A study conducted by the Cincinnati Children’s Hospital Medical Center (CCHMC) [...]

2022-06-16T20:30:41-07:00June 16th, 2022|

COVID-19 In the lab: A conversation with an infectious disease researcher during an active pandemic

SARS-CoV-2, the virus responsible for the disease referred to as COVID-19, has swept across the world infecting millions of humans and tragically killing a significant proportion of those infected. COVID-19 has grown from an outbreak to an epidemic and finally a worldwide pandemic at a historic rate. To [...]

2021-01-06T19:10:35-07:00January 6th, 2021|

Nonhuman primate study on early immune response to SARS-CoV-2 points to specific immune cells for vaccine development

A collection of infectious disease researchers at the California National Primate Research Center and the Center for Immunology and Infectious Diseases observed early immune response to SARS-CoV-2 in rhesus macaques. Their findings suggest vaccine developers should focus on promoting specialized immune cells called CD4 T follicular helper (Tfh) cells [...]

2021-01-06T02:03:39-07:00July 21st, 2020|Tags: |

CNPRC Scientist Hartigan-O’Connor Awarded Funding to Optimize Vaccines for Most Susceptible Populations

Dennis Hartigan-O'Connor, M.D., Ph.D. As scientists rush to find a vaccine for COVID-19, CNPRC core scientist, Dennis Hartigan-O’Connor, M.D., Ph.D is working to optimize vaccine technologies to protect high-risk populations. The University of California Office of the President has awarded Hartigan-O’Connor, along with other scientists across UC [...]

2021-01-06T02:04:07-07:00July 6th, 2020|

Researchers Make Major Strides Towards a Vaccine Against the Zika Virus

Although absent from recent news cycles, Zika virus (ZIKV) continues to be a public health emergency and international concern. A collaborative effort between Koen Van Rompay, core scientist with the California National Primate Research Center (CNPRC), Barney Graham (Vaccine Research Institute) and Ted Pierson (National Institute of Allergy and [...]

2021-01-06T02:05:47-07:00December 20th, 2019|

CNPRC Scientists Abroad: Dr. Koen Van Rompay Lectures on Vector Borne Diseases in India

CNPRC core scientist, Dr. Koen Van Rompay was recently invited by the Indian University of Kannur to give a series of lectures. He travelled the state of Kerala hosted by local scientists and educators giving lectures focused on threatening vector borne diseases. Van Rompay took the opportunity to stress [...]

It Takes a Village to Tackle Zika

By Paul Luciw and Koen Van Rompay Emerging infectious pathogens present opportunities for nonhuman primate model building, transmission and pathogenesis research, and development of interventions by drawing on the expertise of several investigators at the California National Primate Research Center (CNPRC) and collaborating affiliate scientists.  Importantly, the previous multi-disciplinary [...]

CNPRC Core Scientist Tapped for Chancellor’s Achievement Award

Media Contact: CNPRC Info (530) 754 4413 (UC Davis) - California National Primate Research Center Core Scientist Dr. Koen Van Rompay was recently honored for his work, both in and out of the lab, with a Chancellor's Achievement Award  in Diversity and Community. Dr. Van Rompay was among [...]

2017-08-30T23:07:05-07:00February 24th, 2017|

NIH Releases NHP Workshop Report

(UC DAVIS, Calif.) – The National Institutes of Health (NIH) released a report today centering on a recent workshop that explored the use of non-human primates (NHPs) in medical research. The workshop, held Sept. 7, 2016, and entitled “Ensuring the Continued Responsible Oversight of Research with Non-Human Primates” brought together [...]

2017-08-30T23:07:05-07:00January 19th, 2017|

CNPRC Puts Call Out for 2017 Pilot Project Letters of Intent

Contact: CNPRC Info (530) 754-4413 (UC DAVIS, Calif.) – The California National Primate Research Center (CNPRC) Pilot Program invites Letters of Intent for pilot project proposals to support basic and translational research using nonhuman primates (rhesus macaque and titi monkeys) for the 2017-2018 funding period.  Pilot projects that address biomedical/translational research topics across [...]

2017-08-30T23:07:05-07:00January 13th, 2017|Tags: |

Fox 40 Talks Zika With Dr. Koen Van Rompay

Media Contact: CNPRC Info (530) 754-4413 Fox 40 cameras visited the California National Primate Research Center on Monday, Sept. 26, 2016, to interview Dr. Koen Van Rompay about the center's Zika Virus Project. Dr. Van Rompay spoke with Fox 40's Joe Khalil about the Zika project and showed him [...]

2016-10-11T18:16:36-07:00September 27th, 2016|Tags: , , |

HIV Vaccine Developed Through Primate Centers Collaboration

Moving towards human clinical trials Over the past 6 years, Drs. Peter Barry and Alice Tarantal, California National Primate Research Center (CNPRC) at UC Davis, have been collaborating with Dr. Louis Picker at Oregon Health Science University (OHSU)–Oregon NPRC to develop and test a vaccine and potential cure for HIV. [...]

Understanding Zika Virus with Nonhuman Primates

Developing a strategy to prevent and treat Zika virus Research is beginning next week at the California National Primate Research Center (CNPRC) at UC Davis to understand Zika virus. Leading the efforts are Drs. Koen Van Rompay, Eliza Bliss-Moreau, Paul Luciw and John H. Morrison at the CNPRC, and Dr. [...]

Mother-to-infant transmission of high-risk infection: new monkey model

Dr. Peter Barry’s innovative research program using the rhesus monkey as a model of CMV infection leads to a successful study in placental transmission Cytomegalovirus (CMV) infection is highly prevalent in humans, infecting from 50-100% of adults around the world. The virus is often contracted through contact with saliva or [...]

Director Morrison: A Leader in Outreach

“There is no question that this is an exciting time for neuroscience. These major projects around the globe give us great opportunities to let the public know about why our work is important.” John Morrison, PhD, is the director of the California National Primate Research Center at the University of [...]

The Challenge of Controlling HIV

A new understanding of how some infants may resist HIV disease When a person is infected with a virus their immune system is normally activated to respond to and control the infection. However, when a person is persistently infected with HIV, the chronic activation and overstimulation of the immune system [...]

MERIT Program Announced at CNPRC

Igniting Novel Research with Current and New Animal Models Drug discovery and innovative therapeutic approaches in the era of personalized medicine requires the use of animal models that closely recapitulate human disease. To address these challenges, the California National Primate Research Center (CNPRC) at UC Davis is initiating the MERIT [...]

CNPRC Study Leads to Meningococcal Vaccine Improvements

On February 12, 2015, CNPRC Affiliate Scientists Drs. Koen Van Rompay, Peter Beernink, and Dan Granoff announced important findings from a pilot project study conducted at the CNPRC on improving the effectiveness of the meningococcal vaccine for prevention of sepsis and meningitis caused by meningococci group B, a rare, and sometimes [...]

Evaluating Measles Vaccine Safety

High rates of non-vaccinated children throughout the US have reached critical numbers of vulnerable individuals, resulting in perfect conditions for a wildfire storm of measles infections, an easily preventable yet highly contagious disease. More than 120 confirmed cases of measles have been reported in 17 states and the District of [...]

2017-08-30T23:07:09-07:00February 18th, 2015|Tags: , , , , , |
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