Infectious Diseases

//Infectious Diseases

Why Primate Models Matter

Scientists discuss the importance of primate models for advancing knowledge in biomedical and biological research. Presenting an honest, forthright discussion of the ethical considerations of using nonhuman primates (NHP) in research, and demonstrating the vital role NHP have played in many of the medical and scientific advances of the past [...]

2017-08-30T23:07:10+00:00April 15th, 2014|Tags: , |

Vaccine Fends off Virus that Strikes Weak Immune Systems

An experimental vaccine modeling human cytomegalovirus (HCMV) infection — which can endanger developing fetuses, transplant recipients, patients co-infected with HIV and others who have a weakened immune system — proved safe and effective in research conducted at the CNPRC using the rhesus macaque model. A team of scientists from the [...]

2017-08-30T23:07:10+00:00November 8th, 2013|Tags: , |

Influenza Vaccine: Dramatic Increase in Protection of Aged Animals

The flu season can be deadly for thousands of elderly people each year. There is a critical public health need to improve the effectiveness of influenza vaccines. Seminal research results were recently released by Drs. Chris Miller, DVM, PhD, CNPRC Core Scientist, and Tim Carroll, PhD, Post-doctoral scholar at the [...]

2017-08-30T23:07:10+00:00November 5th, 2013|Tags: , , , |

Tenofovir: Prophylaxis for HIV Prevention

Tenofovir (Viread), an antiretroviral HIV drug first shown by the CNPRC to be safe and effective in treating monkeys that were infected with SIV (Simian Immunodeficiency Virus), has once again been used as the key ingredient in a pair of successful HIV preventative studies. The two new studies, by the [...]

2017-10-03T18:15:38+00:00July 14th, 2012|Tags: , , |

Better Understanding of HIV and Immune System Battle

The GI tract is considered a major 'battlefield' between the immune system and HIV. The intestinal mucosa is the site of early infection and aggressive transmission for HIV, making it the first line of defense against the infection. A better understanding of what happens in the GI tract may lead [...]

2017-08-30T23:07:10+00:00March 2nd, 2012|Tags: , , , |