Lower urinary tract (LUT) dysfunction is prevalent in older adults. Clinical manifestations include urinary retention, incontinence and recurrent urinary tract infections. Bladder catheters and increased risk for infections requiring outpatient antibiotic treatment or hospitalization frequently result. This is often followed by the loss of independence and the need for [...]
The California National Primate Research Center is pleased to announce the 2023-2024 CNPRC Pilot Research Program recipients. Every year the CNPRC awards pilot research grants focusing on nonhuman primate (NHP) models of human disease. This award aims to explore innovative areas of NHP research and generate preliminary data to [...]
Image of Coppery Titi Monkey. Photo by Kathy West. Monkey Speed-Dating: The Power of First Impressions Just how important are first impressions? Using a speed-dating model, student researcher Alexander Baxter, explored the significance of first impressions in humans and nonhuman primates. The work published in [...]
CNPRC Pilot Research Project Spotlight: The Impact of Age on COVID Response In the spring of 2020, SARS-CoV-2 swept across the world, and scientists everywhere immediately jumped into action. Questions from how the virus spread, to what the infection does to the human body, to who [...]
UC Davis Researchers Awarded $3.5 Million to Study Disease Causing Vision Loss in Children Autosomal dominant optic atrophy (ADOA) is a rare genetic disease that causes progressive and irreversible vision loss in both eyes starting in the first decade of life. There is currently no treatment [...]
The 40th Annual Symposium on Nonhuman Primate Models for AIDS will take place on October 10-13, 2023, at University of California Davis Activities and Recreation Center in Davis, California. Registration is now open! The 40th annual Symposium will be a unique, world-class [...]
Biological and Behavioral Responses to Intranasal Oxytocin A series of studies published by Dr. Karen Bales’ lab at the California National Primate Research Center revealed that chronic intranasal oxytocin (OT) produces sex-specific biological and behavioral responses in titi monkeys, a monogamous nonhuman primate. Karen Bales [...]
Experimental COVID-19 Vaccine Offers Long-Term Protection Against Severe Disease Two-dose vaccines provide protection against lung disease in rhesus macaques one year after they were vaccinated as infants, a new study shows. The work, published in Science Translational MedicineDec. 1, is a follow-up to a 2021 studying [...]
Presence of SARS-CoV-2 in the brain induces neuroinflammation and disruption of the olfactory cortex in rhesus macaques (Danielle Beckman, CNPRC) COVID-19 Virus Infects Neurons, Induces Inflammation in the Brain by Logan Savidge SARS-CoV-2, the COVID-19 virus, caused significant neuron damage and inflammation within [...]
Wildfire Smoke Exposure in Early Pregnancy Affects Infant Monkey Behavior by Andy Fell Infant monkeys conceived while their mothers were naturally exposed to wildfire smoke show behavioral changes compared to animals conceived days later, according to a new study from researchers at the California [...]
Can Early Life Exposure to Wildfire Smoke Alter Our Genes? Early life wildfire smoke exposure led to long-term changes in genes impacting nervous and immune systems in rhesus macaques, according to research from the California National Primate Research Center (CNPRC) at the University of California, Davis. [...]
‘Life of a Neuron’: A Collaboration Between Scientists and Artists UC Davis Faculty Participating in D.C. Exhibition by Logan Savidge We tend to dichotomize the rational approach of scientific methodology and the creativity of artistic expression. However, the two are much more overlapping than we give [...]
Antibody Treatment Prevents Inflammation in Lungs, Nervous System in Macaques With SARS-CoV-2 by Andy Fell Monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from disease due to SARS-CoV-2 and reduced signs of inflammation, including in cerebrospinal fluid, according to a new study from researchers at the University [...]
Dennis Hartigan-O'Connor, M.D., Ph.D. As scientists rush to find a vaccine for COVID-19, CNPRC core scientist, Dennis Hartigan-O’Connor, M.D., Ph.D is working to optimize vaccine technologies to protect high-risk populations. The University of California Office of the President has awarded Hartigan-O’Connor, along with other scientists across UC [...]
It may surprise people to learn that the measles not only affects humans: it also poses a threat to non-human primates. There are many non-human primates currently living in the country for research, rehabilitation, and conservation purposes. With over 4000 monkeys here at the California National Primate Research Center [...]
Subclinical, persistent viral infections, including those caused by cytomegalovirus (CMV), are highly prevalent in humans. Rocha et al. (e00167-18) found that subclinical CMV infection of rhesus macaques is associated with significantly altered gut microbiota and increased host immune cell numbers and activation. These alterations occur predominantly in an outdoor [...]
Uncovering the neurobiology of social bonding in monogamous primate species Media contact: CNPRC Info 530 754 4413 (UC Davis) - It’s perhaps one of the most common emotions to feel in a relationship, but one that’s virtually untouched when it comes to studying relationships in monogamous primate species. [...]
Media Contact: CNPRC Info (UC Davis) - The recent wildfires in Sonoma, Napa, Solano and Yuba counties have caused air quality to deteriorate throughout Northern California putting thousands of people at risk of potential health problems from the smoke. In this edition of Capital Public Radio's Insight, host Beth [...]
In this edition of the California National Primate Research Center's "Monkey Talk" podcast, we chat with Dr. Jamartin Sihite, the executive director of the Borneo Orangutan Survival Foundation (BOSF) about the incredible work they do to rehabilitate orangutans and prepare them for release into the jungle. The [...]
Media Contact: CNPRC Info, 530-754-4413 (UC Davis) - Dr. Glenn Yiu, MD PhD, Assistant Professor of Ophthalmology at UC Davis School of Medicine, is one of five recipients of the 2017-2018 CNPRC Pilot Research Program award. Doctor Yiu’s laboratory focuses on understanding age-related macular degeneration (AMD), which is the leading cause of vision loss in the [...]
