Presence of SARS-CoV-2 in the brain induces neuroinflammation and disruption of the olfactory cortex in rhesus macaques (Danielle Beckman, CNPRC) COVID-19 Virus Infects Neurons, Induces Inflammation in the Brain by Logan Savidge SARS-CoV-2, the COVID-19 virus, caused significant neuron damage and inflammation within [...]
Antibiotic Exposure During Infancy Remodels Immune Response to Respiratory Pathogens Infants are commonly exposed to and treated with antibiotics during the birthing process. However, new research in nonhuman primates may change the way doctors approach antibiotic treatment. A study conducted by the Cincinnati Children’s Hospital Medical Center (CCHMC) [...]
Wildfire Smoke Exposure in Early Pregnancy Affects Infant Monkey Behavior by Andy Fell Infant monkeys conceived while their mothers were naturally exposed to wildfire smoke show behavioral changes compared to animals conceived days later, according to a new study from researchers at the California [...]
Can Early Life Exposure to Wildfire Smoke Alter Our Genes? Early life wildfire smoke exposure led to long-term changes in genes impacting nervous and immune systems in rhesus macaques, according to research from the California National Primate Research Center (CNPRC) at the University of California, Davis. [...]
‘Life of a Neuron’: A Collaboration Between Scientists and Artists UC Davis Faculty Participating in D.C. Exhibition by Logan Savidge We tend to dichotomize the rational approach of scientific methodology and the creativity of artistic expression. However, the two are much more overlapping than we give [...]
Antibody Treatment Prevents Inflammation in Lungs, Nervous System in Macaques With SARS-CoV-2 by Andy Fell Monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from disease due to SARS-CoV-2 and reduced signs of inflammation, including in cerebrospinal fluid, according to a new study from researchers at the University [...]
SARS-CoV-2, the virus responsible for the disease referred to as COVID-19, has swept across the world infecting millions of humans and tragically killing a significant proportion of those infected. COVID-19 has grown from an outbreak to an epidemic and finally a worldwide pandemic at a historic rate. To [...]
Translational animal models are a necessary step to uncovering the biological basis of human disorders like Autism Spectrum Disorder (ASD) which affects 1 in every 54 children in the United States. Kate Talbot, Ph.D. and her colleagues in the Neuroscience and Behavior Unit at the California National Research Primate [...]
A collection of infectious disease researchers at the California National Primate Research Center and the Center for Immunology and Infectious Diseases observed early immune response to SARS-CoV-2 in rhesus macaques. Their findings suggest vaccine developers should focus on promoting specialized immune cells called CD4 T follicular helper (Tfh) cells [...]
Dennis Hartigan-O'Connor, M.D., Ph.D. As scientists rush to find a vaccine for COVID-19, CNPRC core scientist, Dennis Hartigan-O’Connor, M.D., Ph.D is working to optimize vaccine technologies to protect high-risk populations. The University of California Office of the President has awarded Hartigan-O’Connor, along with other scientists across UC [...]
Collaborative efforts from Peter Havel, DVM, PhD with UC Davis and the California National Primate Research Center and Andrew Butler, PhD at the St. Louis School University of Medicine indicate that targeting a protein known as angiopoietin-like protein-3 or ANGPTL3 could be helpful for managing cardiovascular disease. Their results [...]
Lab safety is not the first thing to come to mind when you read about new scientific findings in the news, but it is an integral part of the scientific process. Lab safety not only informs how data is collected, processed, and analyzed, safety protocols allow us to feel [...]
Almost undoubtedly, you can think of five influential and loved women in your life. With those women in mind, consider that one in every five women and one in every ten American men at the age of 45 are at risk of developing Alzheimer’s disease (AD). As the rates [...]
Although absent from recent news cycles, Zika virus (ZIKV) continues to be a public health emergency and international concern. A collaborative effort between Koen Van Rompay, core scientist with the California National Primate Research Center (CNPRC), Barney Graham (Vaccine Research Institute) and Ted Pierson (National Institute of Allergy and [...]
Amongst the thousands of posters, talks, and endless networking, attendees at the 2019 Society for Neuroscience meeting enjoyed a sneak peek of a new interactive art exhibit. Neuro Space is the real-life expression of director John Morrison's imagination. Following the release of one of his previous collaborative projects, BrainFacts.org, Morrison [...]
The UC Davis Environmental Health Sciences awarded California National Primate Research Center (CNPRC) core scientist, Dr. Hong Ji their 2019-2020 scholar award. Her application to study epigenetics as the link between air pollutant exposures during development and long-term side effects on the lungs will significantly contribute to our knowledge [...]
CNPRC core scientist, Dr. Koen Van Rompay was recently invited by the Indian University of Kannur to give a series of lectures. He travelled the state of Kerala hosted by local scientists and educators giving lectures focused on threatening vector borne diseases. Van Rompay took the opportunity to stress [...]
A new understanding of interactions within our microbiome is revealing the elusive cause of ulcerative colitis through the study of a nonhuman primate disorder, idiopathic chronic diarrhea (ICD). ICD affects 3-5% of all captive macaque monkeys and researchers believe wild macaques could be affected at similar rates. ICD is [...]
It may surprise people to learn that the measles not only affects humans: it also poses a threat to non-human primates. There are many non-human primates currently living in the country for research, rehabilitation, and conservation purposes. With over 4000 monkeys here at the California National Primate Research Center [...]
Subclinical, persistent viral infections, including those caused by cytomegalovirus (CMV), are highly prevalent in humans. Rocha et al. (e00167-18) found that subclinical CMV infection of rhesus macaques is associated with significantly altered gut microbiota and increased host immune cell numbers and activation. These alterations occur predominantly in an outdoor [...]
