The CNPRC’s large colony of domestically bred rhesus macaques allows us to study infectious disease across the complete lifespan, from gestation to geriatric. Preclinical research performed in nonhuman primates provides the crucial proof-of-concept and scientific foundation to test new strategies in human clinical trials. This is extremely important in the study of pharmacology and therapeutics during pregnancy, infancy, and throughout childhood.
Basic and translational research in infectious diseases is integrated and synergistic with other research areas (including immunology, pharmacology, pathology, biology, neuroscience) at the CNPRC, the UC Davis School of Medicine, the UC Davis School of Veterinary Medicine and other institutions. The CNPRC has a proven track-record of R&D partnerships with biotech and pharmaceutical companies to help move novel products through the pipeline of drug development towards clinical trials and approval. These preclinical studies can be performed under GLP protocols.
Examples of Nonhuman Primate Models for Infectious Disease include:
- Cytomegalovirus (CMV)
- Herpes simplex virus (HSV)
- Helicobacter pylori
- Zika virus