Open date: Feb 1, 2022
Initial review date: Feb 16, 2022
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.
Final date: Jun 30, 2022
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Dr. John H. Morrison, Professor of Neurology and Director of the California National Primate Research Center (CNPRC), is seeking to hire a postdoctoral employee, 100% time for the duration of two years with the possibility of extension. The postdoctoral employee will be expected to participate in our research program investigating the synaptic and cellular basis of tau protein pathology as it relates to cognition and brain function in a rhesus monkey model. The overall goal of this program is to establish a novel model for tau neuropathology and assessment of neuropathological and cognitive endpoints in a monkey model, to develop more translationally relevant animal models of Alzheimer’s disease and facilitate both understanding of underlying pathological mechanisms as well as development of novel treatments. In addition to the microscopic assessment of neuropathology, biological samples (blood, cerebrospinal fluid) will be collected and examined for biomarkers of inflammation and neurodegeneration, behavioral testing will be performed to assess cognitive decline, and concurrent neuroimaging studies will be carried out to ascertain whole-brain measures. The postdoctoral researcher will contribute to, and be involved in, all aspects of the research process including study design, protocol development, data collection, sample processing, data analysis, assay work, and writing and publication of research reports and reviews. While molecular approaches are being pursued, most of the lab’s work involves high resolution quantitative microscopy to reveal both synaptic and cellular alterations that are predictive of cognitive decline. Behavioral and in vivo imaging approaches are also employed. Although the primary role of this researcher will be in the analysis of neuroimaging data, fluid biomarkers, and neuroanatomical data, significant opportunities exist for cross-training in cognitive testing aspects of the project. An important aspect of this position will be project management and coordination between the onsite staff and offsite collaborators. The CNPRC, Department of Neurology, and Center for Neuroscience converge to provide an outstanding training opportunity in Dr. Morrison’s laboratory for neuroscientists at multiple stages of development. Applicants must have a Ph.D. in cellular or systems neuroscience, cell biology, biochemistry, molecular biology or related scientific field. It is preferable that the successful applicant has experience with either 1) quantitative microscopy or 2) biochemical analyses of brain tissue. The applicant must have excellent communication skills and have the motivation to pursue and drive projects independently. Candidates should be willing to apply for independent funding.Your Content Goes Here